DNA-binding specificity changes in the evolution of forkhead transcription factors
The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF) families. The forkhead family of TFs, defined by a highly conserved winged helix DNA-binding domain (DBD), has diverged into dozens of subfamilies in animals, fungi, and relate...
Main Authors: | Nakagawa, So, Gisselbrecht, Stephen S., Rogers, Julia M., Hartl, Daniel L., Bulyk, Martha L. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
|
Online Access: | http://hdl.handle.net/1721.1/88252 |
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