Reduction of Human Defensin 5 Affords a High-Affinity Zinc-Chelating Peptide
Human defensin 5 (HD5) is a 32-residue cysteine-rich host-defense peptide that exhibits three disulfide bonds in the oxidized form (HD5[subscript ox]). It is abundant in small intestinal Paneth cells, which release HD5 into the intestinal lumen and house a labile Zn(II) store of unknown function. He...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Chemical Society (ACS)
2014
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| Online Access: | http://hdl.handle.net/1721.1/88524 https://orcid.org/0000-0002-6153-8803 https://orcid.org/0000-0002-6426-2291 |