Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response

Objective: To investigate the role of obesity-associated inflammation and immune modulation in gastric carcinogenesis during Helicobacter-induced chronic gastric inflammation. Design: C57BL/6 male mice were infected with H felis and placed on a high-fat diet (45% calories from fat). Study animals...

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Bibliographic Details
Main Authors: Ericksen, Russell E., Rose, Shannon, Westphalen, Christoph Benedikt, Shibata, Wataru, Muthupalani, Sureshkumar, Tailor, Yagnesh, Friedman, Richard A., Han, Weiping, Fox, James G., Ferrante, Anthony W., Wang, Timothy C.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: BMJ Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/88720
https://orcid.org/0000-0001-9307-6116