Benzannulation via the Reaction of Ynamides and Vinylketenes. Application to the Synthesis of Highly Substituted Indoles
A two-stage “tandem strategy” for the synthesis of indoles with a high level of substitution on the six-membered ring is described. Benzannulation based on the reaction of cyclobutenones with ynamides proceeds via a cascade of four pericyclic reactions to produce multiply substituted aniline derivat...
Main Authors: | Lam, Tin Yiu, Wang, Yu-Pu, Danheiser, Rick Lane |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2014
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Online Access: | http://hdl.handle.net/1721.1/88725 https://orcid.org/0000-0002-9812-206X https://orcid.org/0000-0001-5002-2230 |
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