Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3

The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes. Although MAPKs have been intensely studied, identification of their substrates remains challenging. We ha...

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Bibliographic Details
Main Authors: Carlson, Scott M., Chouinard, Candace R., Labadorf, Adam, Lam, Carol J., Schmelzle, Katrin, Fraenkel, Ernest, White, Forest M.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/88730
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0001-9249-8181