Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds

Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds

Objective: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though the mechanisms by which these effects are mediated are not well understood. We tested the hypothesis that the addition of Dex to chondrogenic m...

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Bibliographic Details
Main Authors: Florine, Emily Marie, Miller, Rachel Elizabeth, Porter, Ryan M., Evans, Christopher H., Kurz, Bodo, Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:en_US
Published: Sage Publications 2014
Online Access:http://hdl.handle.net/1721.1/88973
https://orcid.org/0000-0002-4942-3456
https://orcid.org/0000-0002-5770-838X

Internet

http://hdl.handle.net/1721.1/88973
https://orcid.org/0000-0002-4942-3456
https://orcid.org/0000-0002-5770-838X

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