The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation

The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation

Patients with lung cancer often present with metastatic disease and therefore have a very poor prognosis. The recent discovery of several novel ROS receptor tyrosine kinase molecular alterations in non–small cell lung cancer (NSCLC) presents a therapeutic opportunity for the development of new targe...

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Bibliographic Details
Main Authors: Johnson, Hannah, White, Forest M., Jun, Hyun Jung, Bronson, Roderick T., de Feraudy, Sebastien, Charest, Alain
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for Cancer Research 2014
Online Access:http://hdl.handle.net/1721.1/89034
https://orcid.org/0000-0002-1545-1651

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http://hdl.handle.net/1721.1/89034
https://orcid.org/0000-0002-1545-1651

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