Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals

Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human development and disease, but little is known about their evolutionary history and constraint. Here, we characterize human lincRNA expression patterns in nine tissues across six mammalian species and multiple individuals...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Washietl, Stefan, Kellis, Manolis, Garber, Manuel
Rannpháirtithe: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Formáid: Alt
Teanga:en_US
Foilsithe / Cruthaithe: Cold Spring Harbor Laboratory Press 2014
Rochtain ar líne:http://hdl.handle.net/1721.1/89094