Composability of regulatory sequences controlling transcription and translation in Escherichia coli

Composability of regulatory sequences controlling transcription and translation in Escherichia coli

The inability to predict heterologous gene expression levels precisely hinders our ability to engineer biological systems. Using well-characterized regulatory elements offers a potential solution only if such elements behave predictably when combined. We synthesized 12,563 combinations of common pro...

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Bibliographic Details
Main Authors: Kosuri, Sriram, Goodman, Daniel Bryan, Cambray, Guillaume, Mutalik, Vivek K., Gao, Yuan, Arkin, Adam P., Endy, Drew, Church, George M.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/89095
https://orcid.org/0000-0003-3759-6883

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http://hdl.handle.net/1721.1/89095
https://orcid.org/0000-0003-3759-6883

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