Composability of regulatory sequences controlling transcription and translation in Escherichia coli
The inability to predict heterologous gene expression levels precisely hinders our ability to engineer biological systems. Using well-characterized regulatory elements offers a potential solution only if such elements behave predictably when combined. We synthesized 12,563 combinations of common pro...
Main Authors: | Kosuri, Sriram, Goodman, Daniel Bryan, Cambray, Guillaume, Mutalik, Vivek K., Gao, Yuan, Arkin, Adam P., Endy, Drew, Church, George M. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
|
Online Access: | http://hdl.handle.net/1721.1/89095 https://orcid.org/0000-0003-3759-6883 |
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