A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis

In multicellular organisms, germ cells carry the hereditary material from one generation to the next. Developing germ cells are unipotent gamete precursors, and mature gametes are highly differentiated, specialized cells. However, upon gamete union at fertilization, their genomes drive a totipotent...

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Bibliographic Details
Main Authors: Lesch, Bluma J., Dokshin, Gregoriy A., Young, Richard A., McCarrey, John R., Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/89096
https://orcid.org/0000-0001-9920-3411
https://orcid.org/0000-0001-8855-8647