A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis
In multicellular organisms, germ cells carry the hereditary material from one generation to the next. Developing germ cells are unipotent gamete precursors, and mature gametes are highly differentiated, specialized cells. However, upon gamete union at fertilization, their genomes drive a totipotent...
Main Authors: | Lesch, Bluma J., Dokshin, Gregoriy A., Young, Richard A., McCarrey, John R., Page, David C |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/89096 https://orcid.org/0000-0001-9920-3411 https://orcid.org/0000-0001-8855-8647 |
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