Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Nanoparticle-mediated siRNA delivery is a complex process that requires transport across numerous extracellular and intracellular barriers. As such, the development of nanoparticles for efficient delivery would benefit from an understanding of how parameters associated with these barriers relate to...

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Bibliographic Details
Main Authors: Alabi, Christopher A., Sahay, Gaurav, Yin, Hao, Luly, Kathryn M., Anderson, Daniel Griffith, Love, Kevin T, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/89097
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793
https://orcid.org/0000-0003-4255-0492