Regulation of glutamate receptor internalization by the spine cytoskeleton is mediated by its PKA-dependent association with CPG2

A key neuronal mechanism for adjusting excitatory synaptic strength is clathrin-mediated endocytosis of postsynaptic glutamate receptors (GluRs). The actin cytoskeleton is critical for clathrin-mediated endocytosis, yet we lack a mechanistic understanding of its interaction with the endocytic proces...

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Bibliographic Details
Main Authors: Loebrich, Sven, Djukic, Biljana, Tong, Zachary J., Cottrell, Jeffrey R., Turrigiano, Gina G., Nedivi, Elly
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/89118
https://orcid.org/0000-0002-1710-0767