The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia
The oncogenic transcription factor TAL1/SCL is aberrantly expressed in 60% of cases of human T cell acute lymphoblastic leukemia (T-ALL) and initiates T-ALL in mouse models. By performing global microRNA (miRNA) expression profiling after depletion of TAL1, together with genome-wide analysis of TAL1...
Những tác giả chính: | , , , , , , , , , , , , |
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Tác giả khác: | |
Định dạng: | Bài viết |
Ngôn ngữ: | en_US |
Được phát hành: |
Rockefeller University Press
2014
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Truy cập trực tuyến: | http://hdl.handle.net/1721.1/89125 https://orcid.org/0000-0001-8855-8647 |