Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression

Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression

Activity of glycogen synthase kinase-3β (GSK-3β) is required for long-term depression (LTD) via molecular mechanisms that are incompletely understood. Here, we report that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that promotes synaptic strength, is phosphorylated on threoni...

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Bibliographic Details
Main Authors: Nelson, Christopher D., Kim, Myung Jong, Hsin, Honor, Chen, Yelin, Sheng, Morgan
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:en_US
Published: Society for Neuroscience 2014
Online Access:http://hdl.handle.net/1721.1/89128

Internet

http://hdl.handle.net/1721.1/89128

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