Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

Metabolic syndrome describes a set of obesity-related disorders that increase diabetes, cardiovascular, and mortality risk. Studies of liver-specific protein-tyrosine phosphatase 1b (PTP1b) deletion mice (L-PTP1b[superscript −/−]) suggest that hepatic PTP1b inhibition would mitigate metabolic-syndro...

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Main Authors: Miraldi, Emily Rae, Sharfi, Hadar, Friedline, Randall H., Johnson, Hannah, Zhang, Tejia, Lau, Ken S., Ko, Hwi Jin, Curran, Timothy G., Haigis, Kevin M., Yaffe, Michael B., Bonneau, Richard, Lauffenburger, Douglas A., Kahn, Barbara B., Kim, Jason K., Neel, Benjamin G., Saghatelian, Alan, White, Forest M.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2014
Online Access:http://hdl.handle.net/1721.1/89179
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

Internet

http://hdl.handle.net/1721.1/89179
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

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