Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice

Metabolic syndrome describes a set of obesity-related disorders that increase diabetes, cardiovascular, and mortality risk. Studies of liver-specific protein-tyrosine phosphatase 1b (PTP1b) deletion mice (L-PTP1b[superscript −/−]) suggest that hepatic PTP1b inhibition would mitigate metabolic-syndro...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Miraldi, Emily Rae, Sharfi, Hadar, Friedline, Randall H., Johnson, Hannah, Zhang, Tejia, Lau, Ken S., Ko, Hwi Jin, Curran, Timothy G., Haigis, Kevin M., Yaffe, Michael B., Bonneau, Richard, Lauffenburger, Douglas A., Kahn, Barbara B., Kim, Jason K., Neel, Benjamin G., Saghatelian, Alan, White, Forest M.
מחברים אחרים: Massachusetts Institute of Technology. Computational and Systems Biology Program
פורמט: Article
שפה:en_US
יצא לאור: Royal Society of Chemistry 2014
גישה מקוונת:http://hdl.handle.net/1721.1/89179
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

אינטרנט

http://hdl.handle.net/1721.1/89179
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

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