High-Throughput Mutiplexed Protease Activity Measurement Using a Droplet Based Microfluidic Platform with Picoinjector

In this study, we integrated several components, including a droplet generator, a pico-injector, and an analytical inference technique, Proteolytic Activity Matrix Analysis (PrAMA), to create a platform for assessing multiple specific protease activity assays with minimal liquid handling and sample-...

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Detalhes bibliográficos
Principais autores: Chen, Chia-Hung, Miller, Miles Aaron, Sarkar, Aniruddh, Beste, Michael T., Lauffenburger, Douglas A., Griffith, Linda G., Han, Jongyoon
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: 2014
Acesso em linha:http://hdl.handle.net/1721.1/89199
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0001-7215-1439