Calcium Causes a Conformational Change in Lamin A Tail Domain that Promotes Farnesyl-Mediated Membrane Association

Calcium Causes a Conformational Change in Lamin A Tail Domain that Promotes Farnesyl-Mediated Membrane Association

Lamin proteins contribute to nuclear structure and function, primarily at the inner nuclear membrane. The posttranslational processing pathway of lamin A includes farnesylation of the C-terminus, likely to increase membrane association, and subsequent proteolytic cleavage of the C-terminus. Hutchins...

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Bibliographic Details
Main Authors: Kalinowski, Agnieszka, Qin, Zhao, Coffey, Kelli, Kodali, Ravi, Buehler, Markus J., Dahl, Kris Noel, Losche, Mathias
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/89214
https://orcid.org/0000-0002-4173-9659

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http://hdl.handle.net/1721.1/89214
https://orcid.org/0000-0002-4173-9659

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