Age- and diabetes-related nonenzymatic crosslinks in collagen fibrils: Candidate amino acids involved in Advanced Glycation End-products

Ageing and diabetes share a common deleterious phenomenon, the formation of Advanced Glycation Endproducts (AGEs), which accumulate predominantly in collagen due to its low turnover. Though the general picture of glycation has been identified, the detailed knowledge of which collagen amino acids are...

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Bibliographic Details
Main Authors: Gautieri, Alfonso, Redaelli, Alberto, Vesentini, Simone, Buehler, Markus J
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/89215
https://orcid.org/0000-0003-4540-3789
https://orcid.org/0000-0002-4173-9659