Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4[superscript +] Effector Memory T Cells

Genome-wide association studies (GWAS) and subsequent dense-genotyping of associated loci identified over a hundred single-nucleotide polymorphism (SNP) variants associated with the risk of rheumatoid arthritis (RA), type 1 diabetes (T1D), and celiac disease (CeD). Immunological and genetic studies...

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Main Authors: Hu, Xinli, Kim, Hyun, Raj, Towfique, Brennan, Patrick J., Trynka, Gosia, Teslovich, Nikola, Slowikowski, Kamil, Chen, Wei-Min, Onengut-Gumuscu, Suna, Baecher-Allan, Clare, De Jager, Philip L., Rich, Stephen S., Stranger, Barbara E., Brenner, Michael B., Raychaudhuri, Soumya
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/1721.1/89229
https://orcid.org/0000-0002-7887-4301