Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions
A bias towards angiogenesis from the venous circulation has long been known, but its cause remains unclear. Here we explore the possibility that high interstitial pressure in tumors and the resultant net filtration pressure gradient that would induce flow from the interstitium into the venous circul...
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Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry
2014
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Online Access: | http://hdl.handle.net/1721.1/89235 https://orcid.org/0000-0002-7232-304X |