Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions

A bias towards angiogenesis from the venous circulation has long been known, but its cause remains unclear. Here we explore the possibility that high interstitial pressure in tumors and the resultant net filtration pressure gradient that would induce flow from the interstitium into the venous circul...

Full description

Bibliographic Details
Main Authors: Vickerman, Vernella, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2014
Online Access:http://hdl.handle.net/1721.1/89235
https://orcid.org/0000-0002-7232-304X

Similar Items