Neddylation dysfunction in Alzheimer's disease

Ubiquitin-dependent proteolysis is a major mechanism that downregulates misfolded proteins or those that have finished a programmed task. In the last two decades, neddylation has emerged as a major regulatory pathway for ubiquitination. Central to the neddylation pathway is the amyloid precursor pro...

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Bibliographic Details
Main Authors: Chen, Yuzhi, Neve, Rachael L., Liu, Helena
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: John Wiley & Sons, Inc 2014
Online Access:http://hdl.handle.net/1721.1/89400
https://orcid.org/0000-0002-3854-5968