Neddylation dysfunction in Alzheimer's disease
Ubiquitin-dependent proteolysis is a major mechanism that downregulates misfolded proteins or those that have finished a programmed task. In the last two decades, neddylation has emerged as a major regulatory pathway for ubiquitination. Central to the neddylation pathway is the amyloid precursor pro...
Main Authors: | Chen, Yuzhi, Neve, Rachael L., Liu, Helena |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | en_US |
Published: |
John Wiley & Sons, Inc
2014
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Online Access: | http://hdl.handle.net/1721.1/89400 https://orcid.org/0000-0002-3854-5968 |
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