Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Nucleocytoplasmic transport is mediated by nuclear pore complexes (NPCs) embedded in the nuclear envelope. About 30 different proteins (nucleoporins, nups) arrange around a central eightfold rotational axis to build the modular NPC. Nup188 and Nup192 are related and evolutionary conserved, large nuc...

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Bibliographic Details
Main Authors: Andersen, Kasper R., Onischenko, Evgeny, Tang, Jeffrey H, Kumar, Pravin, Chen, James Z., Ulrich, Alexander, Liphardt, Jan T, Weis, Karsten, Schwartz, Thomas
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2014
Online Access:http://hdl.handle.net/1721.1/89403
https://orcid.org/0000-0001-8012-1512

Internet

http://hdl.handle.net/1721.1/89403
https://orcid.org/0000-0001-8012-1512

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