Hi-C: A Method to Study the Three-dimensional Architecture of Genomes

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes

The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant functional elements, such as promoters and enhancers, into close spatial proximity. Deciphering the relationship between chromosome organization and genome activity will aid in understanding genomic p...

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Bibliographic Details
Main Authors: van Berkum, Nynke L., Lieberman-Aiden, Erez, Williams, Louise, Gnirke, Andreas, Dekker, Job, Imakaev, Maksim Viktorovich, Mirny, Leonid A, Lander, Eric Steven
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: MyJoVE Corporation 2014
Online Access:http://hdl.handle.net/1721.1/89531
https://orcid.org/0000-0002-0785-5410
https://orcid.org/0000-0002-5320-2728

Internet

http://hdl.handle.net/1721.1/89531
https://orcid.org/0000-0002-0785-5410
https://orcid.org/0000-0002-5320-2728

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