Hi-C: A Method to Study the Three-dimensional Architecture of Genomes
The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant functional elements, such as promoters and enhancers, into close spatial proximity. Deciphering the relationship between chromosome organization and genome activity will aid in understanding genomic p...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
MyJoVE Corporation
2014
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| Online Access: | http://hdl.handle.net/1721.1/89531 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-5320-2728 |