Measuring Growth and Gene Expression Dynamics of Tumor-Targeted S. Typhimurium Bacteria

The goal of these experiments is to generate quantitative time-course data on the growth and gene expression dynamics of attenuated S. typhimurium bacterial colonies growing inside tumors. We generated model xenograft tumors in mice by subcutaneous injection of a human ovarian cancer cell line, O...

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Bibliographic Details
Main Authors: Danino, Tal, Prindle, Arthur, Hasty, Jeff, Bhatia, Sangeeta N., Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: MyJoVE Corporation 2014
Online Access:http://hdl.handle.net/1721.1/89635
https://orcid.org/0000-0002-1293-2097
https://orcid.org/0000-0001-7302-4394