Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

Induction of immunity that limits Toxoplasma gondii infection in mice is critically dependent on the activation of the innate immune response. In this study, we investigated the role of cytoplasmic nucleotide-binding domain and leucine-rich repeat containing a pyrin domain (NLRP) inflammasome sensor...

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Bibliographic Details
Main Authors: Gorfu, Gezahegn, Cirelli, Kimberly, Melo, Mariane Bandeira, Mayer-Barber, Katrin, Crown, Devorah, Koller, Beverly H., Masters, Seth, Sher, Alan, Leppla, Stephen H., Moayeri, Mahtab, Saeij, Jeroen, Grigg, Michael E.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Microbiology 2014
Online Access:http://hdl.handle.net/1721.1/89662
https://orcid.org/0000-0003-4583-1118