The SMC Complex MukBEF Recruits Topoisomerase IV to the Origin of Replication Region in Live Escherichia coli

The Escherichia coli structural maintenance of chromosome (SMC) complex, MukBEF, and topoisomerase IV (TopoIV) interact in vitro through a direct contact between the MukB dimerization hinge and the C-terminal domain of ParC, the catalytic subunit of TopoIV. The interaction stimulates catalysis by To...

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Bibliographic Details
Main Authors: Nicolas, Emilien, Upton, Amy L., Uphoff, Stephan, Henry, Olivia, Badrinarayanan, Anjana, Sherratt, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Microbiology 2014
Online Access:http://hdl.handle.net/1721.1/89834
https://orcid.org/0000-0002-6807-6576