On the Minimization of Fluctuations in the Response Times of Autoregulatory Gene Networks

The temporal dynamics of the concentrations of several proteins are tightly regulated, particularly for critical nodes in biological networks such as transcription factors. An important mechanism to control transcription factor levels is through autoregulatory feedback loops where the protein can bi...

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Bibliographic Details
Main Authors: Murugan, Rajamanickam, Kreiman, Gabriel
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/90264