Long-lasting silencing of orexin/hypocretin neurons using archaerhodopsin induces slow-wave sleep in mice

Orexin/hypocretin neurons have a crucial role in the regulation of sleep and wakefulness. Recent optogenetic studies revealed that the activation or inhibition of orexin neuronal activity affects the probability of sleep/wakefulness transition in the acute phase. To expand our understanding of how o...

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Bibliographic Details
Main Authors: Tsunematsu, Tomomi, Tabuchi, Sawako, Tanaka, Kenji F., Tominaga, Makoto, Yamanaka, Akihiro, Boyden, Edward
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/90302
https://orcid.org/0000-0002-0419-3351