Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

Valency requirements for B cell activation upon antigen encounter are poorly understood. OB1 transnuclear B cells express an IgG1 B cell receptor (BCR) specific for ovalbumin (OVA), the epitope of which can be mimicked using short synthetic peptides to allow antigen-specific engagement of the BCR. B...

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Bibliographic Details
Main Authors: Avalos, Ana M., Bilate, Angelina M., Witte, Martin D., Tai, Albert K., He, Jiang, Frushicheva, Maria P., Thill, Peter Daniel, Meyer-Wentrup, Friederike, Theile, Christopher S., Chakraborty, Arup K., Zhuang, Xiaowei, Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Rockefeller University Press 2014
Online Access:http://hdl.handle.net/1721.1/90353
https://orcid.org/0000-0001-6259-8800
https://orcid.org/0000-0002-7487-8858
https://orcid.org/0000-0003-1268-9602
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/90353
https://orcid.org/0000-0001-6259-8800
https://orcid.org/0000-0002-7487-8858
https://orcid.org/0000-0003-1268-9602
https://orcid.org/0000-0002-1090-6071

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