Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance

Diet-induced obesity (DIO) predisposes individuals to insulin resistance, and adipose tissue has a major role in the disease. Insulin resistance can be induced in cultured adipocytes by a variety of treatments, but what aspects of the in vivo responses are captured by these models remains unknown. W...

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Bibliographic Details
Main Authors: Lo, Kinyui Alice, Labadorf, Adam, Kennedy, Norman J., Han, Myoung Sook, Yap, Yoon Sing, Matthews, Bryan, Xin, Xiaofeng, Sun, Lei, Davis, Roger J., Lodish, Harvey F., Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/90558
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-6804-251X