In Silico Modeling of Shear-Stress-Induced Nitric Oxide Production in Endothelial Cells through Systems Biology

In Silico Modeling of Shear-Stress-Induced Nitric Oxide Production in Endothelial Cells through Systems Biology

Nitric oxide (NO) produced by vascular endothelial cells is a potent vasodilator and an antiinflammatory mediator. Regulating production of endothelial-derived NO is a complex undertaking, involving multiple signaling and genetic pathways that are activated by diverse humoral and biomechanical stimu...

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Bibliographic Details
Main Authors: Koo, Andrew Jia-An, Nordsletten, David, Umeton, Renato, Yankama, Beracah, Ayyadurai, V. A. Shiva, Dewey, C. Forbes, Garcia-Cardena, Guillermo
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/90559
https://orcid.org/0000-0001-7387-3572

Internet

http://hdl.handle.net/1721.1/90559
https://orcid.org/0000-0001-7387-3572

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