Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

Filopodia are long plasma membrane extensions involved in the formation of adhesive, contractile, and protrusive actin-based structures in spreading and migrating cells. Whether filopodia formed by different molecular mechanisms equally support these cellular functions is unresolved. We used Enabled...

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Bibliographic Details
Main Authors: Barzik, Melanie, McClain, Leslie Marie, Gupton, Stephanie L., Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Cell Biology 2014
Online Access:http://hdl.handle.net/1721.1/90926
https://orcid.org/0000-0001-6738-2435
https://orcid.org/0000-0003-3214-4554