Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a probe of choice. We explore sortase-mediated tran...

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Bibliographic Details
Main Authors: Wuethrich, Irene, Peeters, Janneke G. C., Blom, Annet E. M., Theile, Christopher S., Li, Zeyang, Spooner, Eric, Ploegh, Hidde, Guimaraes, Carla P.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2014
Online Access:http://hdl.handle.net/1721.1/90948
https://orcid.org/0000-0002-0205-1026
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/90948
https://orcid.org/0000-0002-0205-1026
https://orcid.org/0000-0002-1090-6071

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