Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

Dysfunctions in frontostriatal brain circuits have been implicated in neuropsychiatric disorders, including those characterized by the presence of repetitive behaviors. We developed an optogenetic approach to block repetitive, compulsive behavior in a mouse model in which deletion of the synaptic sc...

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Bibliographic Details
Main Authors: Burguiere, Eric, Monteiro, Patricia, Feng, Guoping, Graybiel, Ann M.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2014
Online Access:http://hdl.handle.net/1721.1/91012
https://orcid.org/0000-0003-3288-4560
https://orcid.org/0000-0002-8021-277X
https://orcid.org/0000-0002-4326-7720

Internet

http://hdl.handle.net/1721.1/91012
https://orcid.org/0000-0003-3288-4560
https://orcid.org/0000-0002-8021-277X
https://orcid.org/0000-0002-4326-7720

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