Matrix Remodeling Maintains ESC Self-Renewal by Activating Stat3

While a variety of natural and synthetic matrices have been used to influence embryonic stem cell (ESC) self-renewal or differentiation, and ESCs also deposit a rich matrix of their own, the mechanisms behind how extracellular matrix affects cell fate are largely unexplored. The ESC matrix is contin...

Full description

Bibliographic Details
Main Authors: Przybyla, Laralynne M., Theunissen, Thorold W., Jaenisch, Rudolf, Voldman, Joel
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Wiley Blackwell 2014
Online Access:http://hdl.handle.net/1721.1/91020
https://orcid.org/0000-0001-8898-2296