Systematic parameter estimation in data-rich environments for cell signalling dynamics

Motivation: Computational models of biological signalling networks, based on ordinary differential equations (ODEs), have generated many insights into cellular dynamics, but the model-building process typically requires estimating rate parameters based on experimentally observed concentrations. New...

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Bibliographic Details
Main Authors: White, Jacob K., Nim, Tri Hieu, Luo, Le, Clement, Marie Veronique, Tucker-Kellogg, Lisa
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Oxford University Press 2014
Online Access:http://hdl.handle.net/1721.1/91023
https://orcid.org/0000-0003-1080-4005