Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery

Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery

The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 and TLR 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidazoquinoline...

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Bibliographic Details
Main Authors: Nguyen, David N., Mahon, Kerry P., Chikh, Ghania, Kim, Phillip, Chung, Hattie, Vicari, Alain P., Love, Kevin T., Goldberg, Michael Solomon, Chen, Steve, Krieg, Arthur M., Chen, Jianzhu, Langer, Robert, Anderson, Daniel Griffith
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/91044
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-5687-6154
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/91044
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-5687-6154
https://orcid.org/0000-0003-4255-0492

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