Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 and TLR 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidazoquinoline...
Main Authors: | Nguyen, David N., Mahon, Kerry P., Chikh, Ghania, Kim, Phillip, Chung, Hattie, Vicari, Alain P., Love, Kevin T., Goldberg, Michael Solomon, Chen, Steve, Krieg, Arthur M., Chen, Jianzhu, Langer, Robert, Anderson, Daniel Griffith |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2014
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Online Access: | http://hdl.handle.net/1721.1/91044 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0002-5687-6154 https://orcid.org/0000-0003-4255-0492 |
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