A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase

A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase

Synthetic genetic systems share resources with the host, including machinery for transcription and translation. Phage RNA polymerases (RNAPs) decouple transcription from the host and generate high expression. However, they can exhibit toxicity and lack accessory proteins (σ factors and activators) t...

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Bibliographic Details
Main Authors: Segall-Shapiro, Thomas Hale, Meyer, Adam J., Ellington, Andrew D., Sontag, Eduardo D., Voigt, Christopher A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: EMBRO Press/Wiley 2014
Online Access:http://hdl.handle.net/1721.1/91241
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0001-9364-6537

Internet

http://hdl.handle.net/1721.1/91241
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0001-9364-6537

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