Distribution-Based Clustering: Using Ecology To Refine the Operational Taxonomic Unit

16S rRNA sequencing, commonly used to survey microbial communities, begins by grouping individual reads into operational taxonomic units (OTUs). There are two major challenges in calling OTUs: identifying bacterial population boundaries and differentiating true diversity from sequencing errors. Curr...

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Bibliographic Details
Main Authors: Preheim, Sarah Pacocha, Perrotta, Allison Rose, Martin-Platero, Antonio M., Gupta, Anika, Alm, Eric J.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Microbiology 2014
Online Access:http://hdl.handle.net/1721.1/91469
https://orcid.org/0000-0001-8294-9364
https://orcid.org/0000-0003-4378-9542