Distribution-Based Clustering: Using Ecology To Refine the Operational Taxonomic Unit
16S rRNA sequencing, commonly used to survey microbial communities, begins by grouping individual reads into operational taxonomic units (OTUs). There are two major challenges in calling OTUs: identifying bacterial population boundaries and differentiating true diversity from sequencing errors. Curr...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Society for Microbiology
2014
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Online Access: | http://hdl.handle.net/1721.1/91469 https://orcid.org/0000-0001-8294-9364 https://orcid.org/0000-0003-4378-9542 |