Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

The capacity to repair different types of DNA damage varies among individuals, making them more or less susceptible to the detrimental health consequences of damage exposures. Current methods for measuring DNA repair capacity (DRC) are relatively labor intensive, often indirect, and usually limited...

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Bibliographic Details
Main Authors: Nagel, Zachary D., Margulies, Carrie Marie, Chaim, Isaac Alexander, McRee, Siobhan K., Mazzucato, Patrizia, Ahmad, Anwaar, Abo, Ryan, Butty, Vincent, Forget, Anthony L., Samson, Leona D.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2014
Online Access:http://hdl.handle.net/1721.1/91471
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0002-1757-4954
https://orcid.org/0000-0002-7112-1454