Rational Design of a Biomimetic Cell Penetrating Peptide Library

Cell penetrating peptides have demonstrated potential to facilitate the cellular delivery of therapeutic molecules. Here we develop a set of 50 cell penetrating peptide based formulations with potential to deliver small interfering RNAs intercellularly. The transfection efficacy of siRNA containing...

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Bibliographic Details
Main Authors: Urbanska, Aleksandra M., Sahay, Gaurav, Jhunjhunwala, Siddharth, Karagiannis, Emmanouil, Anderson, Daniel Griffith, Pelet, Jeisa, Langer, Robert S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2014
Online Access:http://hdl.handle.net/1721.1/91496
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0003-0131-6552
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0003-4255-0492