Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly is a neurodevelopmental disorder causing significantly reduced cerebral cortex size. Many known microcephaly gene products localize to centrosomes, regulating cell fate and proliferation. Here, we identify and characterize a nuclear zinc finger protein, ZNF335/NIF-1, as a causative gene...

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Bibliographic Details
Main Authors: Baltus, Andrew E., Mathew, Rebecca S., Murphy, Elisabeth A., Evrony, Gilad D., Gonzalez, Dilenny M., Wang, Estee P., Marshall-Walker, Christine A., Barry, Brenda J., Murn, Jernej, Tatarakis, Antonis, Mahajan, Muktar A., Samuels, Herbert H., Shi, Yang, Golden, Jeffrey A., Mahajnah, Muhammad, Shenhav, Ruthie, Walsh, Christopher A., Yang, Yawei
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91519

Internet

http://hdl.handle.net/1721.1/91519

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