Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

Microcephaly is a neurodevelopmental disorder causing significantly reduced cerebral cortex size. Many known microcephaly gene products localize to centrosomes, regulating cell fate and proliferation. Here, we identify and characterize a nuclear zinc finger protein, ZNF335/NIF-1, as a causative gene...

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Main Authors: Baltus, Andrew E., Mathew, Rebecca S., Murphy, Elisabeth A., Evrony, Gilad D., Gonzalez, Dilenny M., Wang, Estee P., Marshall-Walker, Christine A., Barry, Brenda J., Murn, Jernej, Tatarakis, Antonis, Mahajan, Muktar A., Samuels, Herbert H., Shi, Yang, Golden, Jeffrey A., Mahajnah, Muhammad, Shenhav, Ruthie, Walsh, Christopher A., Yang, Yawei
其他作者: Harvard University--MIT Division of Health Sciences and Technology
格式: 文件
语言:en_US
出版: Elsevier 2014
在线阅读:http://hdl.handle.net/1721.1/91519

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http://hdl.handle.net/1721.1/91519

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