Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role of Nanog in vivo, we identified a zebrafish Nanog ortholog and found that its...

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Bibliographic Details
Main Authors: Xu, Cong, Fan, Zi Peng, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G., Daley, George Q., Schier, Alexander F., Young, Richard A., Zon, Leonard I., Muller, Patrick, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91520
https://orcid.org/0000-0001-8855-8647